HughesMedicine - Pharmacotherapy Pearls from the Internal Medicine Clinical Pharmacist
Tuesday, August 30, 2016
Warfarin dosing nomogram for initiating therapy
A 60 year old female patient presents to the emergency department with complaints of swelling and pain in her right leg. She recently had her knee replaced and has healed well since the procedure. She has a PMH of HTN and CKD (Stage IV). She has no other complaints at this time. She is diagnosed with a proximal DVT on lower extremity ultrasound and the decision is made to anticoagulate her with warfarin plus a parenteral anticoagulant. Her baseline INR is 1.28. What strategy can we use to initiate her on warfarin to reach a therapeutic INR in a reasonable amount of time without overanticoagulating her?
Recommended for you
-
Let’s start with a patient case. A patient is being treated with methylprednisolone 20 mg IV q6 hours for some inflammatory process and...
-
A 55 year old business executive is being discharged from the hospital after a brief admission for cellulitis. His only PMH is HTN and o...
-
There are many different insulin preparations and supplies available in order to create individualized regimens for patients. Here are s...
-
Daptomycin (Cubicin) is the first antibiotic in a class known as lipopeptides and has a unique mechanism of action. Daptomycin is a large...
-
A 65 year old male is being treated for an infection on his forearm that developed purulent drainage within the last few days. He denies ...
-
Midodrine is a peripherally-acting selective alpha1 receptor agonist . Let's take that sentence apart to see what we should expect ...
-
A 48 year old male is admitted to the hospital after experiencing a fever and malaise for several days. He states that he has some shortn...
-
An elderly male presents to the emergency department with complaints of nausea, vomiting, and diarrhea starting a day and a half ago. The...
-
The American Geriatrics Society (AGS) 2023 updated AGS Beers Criteria ® for potentially inappropriate medication (PIM) use in older adul...
-
Let’s start with a patient case. An elderly patient is admitted through the emergency department with markedly worsening dyspnea and pu...